Evolution is in continuation to get the advanced and betterment for enhancing the quality of life.
Growing teeth is a bioengineering technology with the ultimate goal to create.
Evolutions:-
- British scientists have learned how to grow almost whole, but feeble teeth from single cells.
- Japanese scientists have bred mice almost full new teeth, but without a root.
- Japanese researchers have grown normal-looking teeth with roots from single cells in lab dishes and transplanted them into mice.
In a new breakthrough scientist used primitive cells, not quite as early as stem cells, and injected them into a framework of collagen, the material that holds the body together. After growing them, they found their structures had matured into the components that make teeth, including dentin, enamel, dental pulp, blood vessels, and periodontal ligaments.
They were "arranged appropriately when compared with a natural tooth," the researchers reported in the journal Nature Methods.
The teeth grew and developed normally when transplanted into a mouse, said Dr. Takashi Tsuji (Ph.D) of the Tokyo University of Science in Chiba, Japan and colleagues. Their method was the first to show an entire organ could be replaced using just a few cells. "Stem cell transplantation therapies have been developed to restore the partial loss of organ function”.
"The ultimate goal of regenerative therapy, however, is to develop fully functioning bioengineered organs that can replace lost or damaged organs after disease, injury or aging."
The researchers also dig for "organ germ" – the early cells made using partially differentiated cells called as mesenchymal and epithelial cells. In this case, the cells were taken from what is known as the tooth germ, the little bud that appears before an animal grows a tooth.
"The reconstituted tooth germs in our mouth generates a complete and entirely bioengineered tooth" "This study thus provides the first evidence of a successful reconstitution of an entire organ via the transplantation of bioengineered material,” "Our present findings should also encourage the future development of organ replacement by regenerative therapy."
